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Influenza pandemics occur cyclically because


A) less than 100% of the population is immunized.
B) new strains emerge due to reassortment between bird, swine, and human variants.
C) the vector is seasonal.
D) there are environmental reservoirs that release the virus during particular seasons.

E) A) and B)
F) A) and C)

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A disease that is constantly present in low numbers is called an acute disease.

A) True
B) False

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What measures would be taken if a case of smallpox were recognized in a world traveler after the individual had debarked from Heathrow airport in England following several days of sightseeing in London?

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The World Health Organization (WHO) woul...

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Which of the following shows the correct relationship among the epidemiology terms listed?


A) prevalence > incidence > mortality
B) incidence > prevalence > mortality
C) mortality > morbidity > prevalence
D) mortality > incidence > prevalence

E) A) and C)
F) All of the above

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Upper respiratory infectious agents are commonly transmitted from person to person.

A) True
B) False

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Explain the concept of coevolution in terms of host-pathogen interactions.

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The host and pathogen both evolve and af...

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Which group of organisms is difficult to control through immunization because of their rapid and unpredictable genetic mutations?


A) vector-borne organisms
B) RNA viruses
C) Archaea
D) DNA viruses

E) A) and D)
F) B) and C)

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Why are diseases such as rabies that have a wild animal reservoir so difficult to eradicate while other diseases such as brucellosis that reside in domestic animals have been virtually eradicated.

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The eradication of a disease requires th...

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Potential candidates for biological warfare


A) are generally gram-negative rather than gram-positive.
B) can be virtually any pathogenic bacterium or virus.
C) are eukaryotic rather than prokaryotic.
D) must be genetically engineered to be effective.

E) B) and C)
F) A) and D)

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Changes in food processing and distribution can increase the incidence of new and emerging diseases.

A) True
B) False

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Filoviruses (such as Ebola virus) that cause severe hemorrhagic fevers generally have high ________ but low ________.


A) incidence / prevalence
B) prevalence / mortality
C) mortality / morbidity
D) morbidity / mortality

E) A) and B)
F) C) and D)

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The lower the basic reproduction number of a pathogen, the higher the percentage of immune individuals necessary to provide herd immunity.

A) True
B) False

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What is a/are potential reservoir(s) for the rabies virus?


A) water
B) insects
C) bats
D) fomites

E) B) and C)
F) A) and D)

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The number of ill individuals within a population is referred to as


A) morbidity.
B) mortality.
C) residency.
D) prevalence.

E) B) and D)
F) None of the above

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Influenza pandemics occur periodically due to characteristics of the influenza virus. How did these characteristics, in this case of the H1N1 strain, contribute to the spread of the swine flu pandemic in 2009?


A) The H1N1 virus had a mutation that increased the mortality associated with infection.
B) The H1N1 virus had a mutation that increased the basic reproduction number of the virus.
C) The H1N1 virus underwent a significant antigenic shift compared to other circulating strains of influenza.
D) The H1N1 virus acquired a new gene from pigs that resulted in increased virulence.

E) A) and B)
F) All of the above

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Which of the following are NOT vectors important in disease transmission?


A) fomites
B) insects
C) ticks
D) rodents

E) B) and C)
F) None of the above

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Food and water are considered disease vehicles.

A) True
B) False

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To control a disease in a population, 100% immunization is necessary.

A) True
B) False

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Based on knowing the history of the HIV/AIDS pandemic, and of efforts to track its spread, you can conclude that it is likely that the incidence of HIV/AIDS among transfusion recipients has


A) increased since the discovery of HIV.
B) decreased since the discovery of HIV.
C) remained the same since the discovery of HIV.
D) never been more than a few individuals per year.

E) B) and C)
F) A) and D)

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Over time, the relationship between a pathogen and a naΓ―ve susceptible population tends towards


A) the extinction of the host.
B) the extinction of the pathogen.
C) a balance between host and pathogen such that both are maintained.
D) the extinction of either the host or the pathogen.

E) A) and C)
F) All of the above

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